者主张将脑损伤分为局限性和弥漫性损伤两大类更为实用[3,8]。 总之DAI是常见弥漫性脑损伤,可分为轻、中、重三型,脑震荡和原发脑干损伤被包含其中,且常常与脑皮质挫裂伤伴发,对DAI发病机制的认识,为脑损伤的的诊断和治疗提供了依据,且有望改变现有原发脑损伤的分类方法。 作者单位:姜曙(610041 成都,华西医科大学第一附属医院神经外科) 鞠延(610041 成都,华西医科大学第一附属医院神经外科) 贺民(610041 成都,华西医科大学第一附属医院神经外科) 毛伯镛(610041 成都,华西医科大学第一附属医院神经外科) 参考文献 1,Adams JH, Graham DI, Murray LS, et al. Diffuse axonal injury due to nonmissile head injury in human: an analysis of 45 cases.Ann Neurol,1982,12:557. 2,Gennarelli TA. Mechanisms of cerebral concusion, contusion and other effects of head injury. Youngmans, 1991. 1953-1964. 3,Adams JH, Gennarelli TA, Maxwell WL. Diffuse axonal injury in nonmissile head injury. J Neurosurg Psychiatry, 1991,54:481. 4,Ross DT, Meaney DF, Sabol NK, et al. Distribution of forebrain diffuse axonal injury following inertial closed head injury in miniature swine. Exp Neurol, 1994, 126:291-299. 5,贺晓生,易声禹,章翔,等.脑弥漫性轴索损伤致伤装置的研制和应用.第四军医大学学报, 1998,19: 87-89. 6,Gentleman SM, Robrts GW, Gennareli TA, et al. Axonal injury: a universal consequence of fatal closed head injury. Acta Neuropathol Berl, 1995, 89:537-543. 7,Graham DI, Adams JH, Nicoll JA, et al. The nature, distribution and causes of traumatic brain injury. Brain Pathol, 1995,5:397-406. 8,Meaney DF, Rose DT, Winkelstein BA. Modification of the cortical impact model to produce axonal injury in the rat cerebral cortex. J Neurotrauma, 1994, 11: 599-612.
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